Dehp full form

Di 2-ethylhexyl phthalate DEHP is a man-made chemical. It is a colorless liquid with a slight odor. DEHP is dehp full form throughout the environment at low levels. It gets into the environment mostly through the disposal of plastic waste in landfills.

Federal government websites often end in. The site is secure. Diethylhexyl phthalate DEHP is extensively used as a plasticizer in many products, especially medical devices, furniture materials, cosmetics, and personal care products. Due to the overuse of DEHP in many products, it enters and pollutes the environment through release from industrial settings and plastic waste disposal sites. DEHP can enter the body through inhalation, ingestion, and dermal contact on a daily basis, which has raised some concerns about its safety and its potential effects on human health. The main aim of this review is to give an overview of the endocrine, testicular, ovarian, neural, hepatotoxic, and cardiotoxic effects of DEHP on animal models and humans in vitro and in vivo. Diethylhexyl phthalate DEHP is the most common member of the class of phthalates, which are used as plasticizers in polymer products to make plastic flexible.

Dehp full form

If you have any questions, comments, or concerns about the content of this page, please contact us. Di 2-ethylhexyl phthalate DEHP. DEHP is on the Proposition 65 list because it can cause cancer and birth defects or other reproductive harm. Exposure to DEHP may increase the risk of cancer, and may also harm the male reproductive system. Exposure to DEHP during pregnancy may affect the development of the child. Proposition 65 requires businesses to determine if they must provide a warning about exposure to listed chemicals. What is DEHP? DEHP belongs to a family of chemicals called phthalates, which are added to some plastics to make them flexible. In the past, DEHP was one of the phthalates most frequently used in plastic products, but its use has decreased in recent years for a variety of reasons. DEHP is still used in various types of plastic consumer products, including some: Shower curtains, furniture, and automobile upholstery, garden hoses, floor tiles, and coverings on wires and cables. Rainwear and shoes. Lunchboxes, binders, and backpacks. Plastic food packaging materials. Medical devices and equipment, including some types of blood and intravenous solution bags, tubing for dialysis, feeding tubes, oxygen masks, and surgical gloves.

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DEHP is the most common member of the class of phthalates , which are used as plasticizers. It is the diester of phthalic acid and the branched-chain 2-ethylhexanol. This colorless viscous liquid is soluble in oil, but not in water. Di 2-ethylhexyl phthalate is produced commercially by the reaction of excess 2-ethylhexanol with phthalic anhydride in the presence of an acid catalyst such as sulfuric acid or para -toluenesulfonic acid. It was first produced in commercial quantities in Japan circa and in the United States in DEHP has two stereocenters, [8] located at the carbon atoms carrying the ethyl groups.

Chemical Classification: Phthalates. Summary: Di 2-ethylhexyl phthlate DEHP is a manufactured chemical that is commonly added to plastics to make them flexible. DEHP is a colorless liquid with almost no odor. DEHP is present in plastic products such as wall coverings, tablecloths, floor tiles, furniture upholstery, shower curtains, garden hoses, swimming pool liners, rainwear, baby pants, dolls, some toys, shoes, automobile upholstery and tops, packaging film and sheets, sheathing for wire and cable, medical tubing, and blood storage bags. ToxFAQs - Fact sheet that answers the most frequently asked questions about a contaminant and its health effects. Toxicological Profile - Succinctly characterizes the toxicologic and adverse health effects information for a hazardous substance. ToxGuide pdf icon [ KB] - Quick reference guide providing information such as chemical and physical properties, sources of exposure, routes of exposure, minimal risk levels, children's health, and health effects for a substance.

Dehp full form

Federal government websites often end in. The site is secure. Diethylhexyl phthalate DEHP is extensively used as a plasticizer in many products, especially medical devices, furniture materials, cosmetics, and personal care products. Due to the overuse of DEHP in many products, it enters and pollutes the environment through release from industrial settings and plastic waste disposal sites. DEHP can enter the body through inhalation, ingestion, and dermal contact on a daily basis, which has raised some concerns about its safety and its potential effects on human health. The main aim of this review is to give an overview of the endocrine, testicular, ovarian, neural, hepatotoxic, and cardiotoxic effects of DEHP on animal models and humans in vitro and in vivo. Diethylhexyl phthalate DEHP is the most common member of the class of phthalates, which are used as plasticizers in polymer products to make plastic flexible.

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Choi K. Di 2-ethylhexyl phthalate inhibits growth of mouse ovarian antral follicles through an oxidative stress pathway. Download as PDF Printable version. Food and Chemical Toxicology. BMC Women's Health. Infobox references. Erkekoglu P. It has been identified that DEHP can be spread to heart tissue. Prenatal phthalate exposure has been shown to be associated with lower levels of reproductive function in adolescent males. During the process of spermatogenesis, zinc will be incorporated in the germ cells, and there is a gradual increase in the zinc concentrations in the testis, which suggests that zinc helps in the maintenance and regulation of sperm motility and spermatogenesis [ 36 ]. It is also used as a hydraulic fluid and as a dielectric fluid in capacitors. Reduced hippocampal dendritic spine density and BDNF expression following acute postnatal exposure to Di 2-Ethylhexyl phthalate in male long evans rats. Effects of di-isononyl phthalate, diethylhexyl phthalate, and clofibrate in cynomolgus monkeys. Critical Reviews in Toxicology.

DEHP is the most common member of the class of phthalates , which are used as plasticizers. It is the diester of phthalic acid and the branched-chain 2-ethylhexanol. This colorless viscous liquid is soluble in oil, but not in water.

Continuous oral exposure to DEHP of rodents can cause hepatomegaly, which is due to hyperplasia and hypertrophy of liver parenchymal cells. Chemical formula. Biomed Res Int. An estimation of the daily intake of di 2-ethylhexyl phthalate DEHP and other phthalates in the general population. Studies in mice have shown other adverse health effects due to DEHP exposure. DEHP treatment of endometrial cells in vitro has been shown to increase ROS, which indicates that DEHP can induce oxidative stress in human endometrial cells [ 60 ] and DEHP-associated endometrial stromal cell alterations may be associated with the progression of the pathogenesis of endometriosis [ 61 ]. Common exposures come from the use of DEHP as a fragrance carrier in cosmetics , personal care products, laundry detergents , colognes, scented candles , and air fresheners. Thus, hospitals have the option of choosing PVC-free medical devices. Skip directly to site content. It was first produced in commercial quantities in Japan circa and in the United States in Also, DEHP caused down regulation of several growth factors, such as angiotensinogen , transforming growth factor-beta , vascular endothelial growth factor C and A , and endothelial Environmental Pollution.