lupron wiki

Lupron wiki

Editor-In-Chief: C. Michael Gibson, M.

Leuprorelin , also known as leuprolide , is a manufactured version of a hormone used to treat prostate cancer , breast cancer , endometriosis , uterine fibroids , as part of transgender hormone therapy , for early puberty , or to perform chemical castration of violent sex offenders. Leuprorelin is in the gonadotropin-releasing hormone GnRH analogue family of medications. Leuprorelin was patented in and approved for medical use in the United States in Leuprorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer and breast cancer. It may also be used for estrogen-dependent conditions such as endometriosis [12] or uterine fibroids. It may be used for precocious puberty in both males and females, [13] and to prevent premature ovulation in cycles of controlled ovarian stimulation for in vitro fertilization IVF.

Lupron wiki

Language Label Description Also known as English leuprolide. PubChem CID. Leuprorelin English. Lupron Depot. World Health Organisation international non-proprietary name. Leuprolide English. Food and Drug Administration. Inxight: Drugs Database. Gonadotropin releasing hormone receptor. Guide to Pharmacology Ligand ID.

Archived from the original on 3 December

Leuprorelin , also known as leuprolide , is a manufactured version of a hormone used to treat prostate cancer , breast cancer , endometriosis , uterine fibroids , as part of transgender hormone therapy , for early puberty , or to perform chemical castration of violent sex offenders. Leuprorelin is in the gonadotropin-releasing hormone GnRH analogue family of medications. Leuprorelin was patented in and approved for medical use in the United States in Leuprorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer and breast cancer. It may also be used for estrogen-dependent conditions such as endometriosis [12] or uterine fibroids. It may be used for precocious puberty in both males and females, [13] and to prevent premature ovulation in cycles of controlled ovarian stimulation for in vitro fertilization IVF. This use is controversial since the Lupron label advises against using the drug when one is considering pregnancy, due to a risk of birth defects.

It helps to slow down testosterone production, which plays a role in the growth of prostate cancer cells. Lupron is a brand name for leuprolide acetate, a luteinizing hormone-releasing hormone LHRH agonist. LHRH is a naturally occurring hormone that stimulates the production of testosterone in the testes. Lupron effectively blocks LHRH, so it reduces the amount of testosterone in your body. Lupron is a type of hormone therapy used to treat prostate cancer, which is powered by testosterone. Male hormones give prostate cancer cells the fuel they need to grow and spread. The goal of hormone treatments, such as Lupron, is to deprive cancer cells of this fuel to slow disease progression. That said, Lupron is not a cure for prostate cancer. Rather, it works to slow down the growth and spread of the cancer.

Lupron wiki

Lupron is a drug doctors prescribe to treat prostate cancer. It works by reducing testosterone levels in the body, slowing cancer growth. Lupron is the brand name for leuprolide acetate. Lupron belongs to a class of drugs called luteinizing hormone-releasing hormone LHRH agonists. These medications block the production of LHRH in the body, which results in the testicles producing less testosterone.

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Archived from the original on 13 June Archived from the original on 8 December Results of testosterone determinations are dependent on assay methodology. Archived from the original on 3 February Archived from the original on 29 July N -[1-[[1-[[1-[[1-[[1-[[1-[[5- diaminomethylideneamino [2- ethylcarbamoyl pyrrolidinyl]oxo-pentan yl]carbamoyl]methyl-butyl]carbamoyl]methyl- butyl]carbamoyl] 4-hydroxyphenyl ethyl] carbamoyl]hydroxy-ethyl]carbamoyl] 1 H -indol yl ethyl]carbamoyl] 3 H -imidazolyl ethyl]oxo- pyrrolidinecarboxamide. Wiktionary 0 entries edit. Reactions considered not drug-related are excluded. Retrieved 17 November Archived from the original PDF on 6 March Leuprorelin , also known as leuprolide , is a manufactured version of a hormone used to treat prostate cancer , breast cancer , endometriosis , uterine fibroids , as part of transgender hormone therapy , for early puberty , or to perform chemical castration of violent sex offenders. Patients may experience worsening of symptoms or onset of new signs and symptoms during the first few weeks of treatment, including bone pain, neuropathy , hematuria , or bladder outlet obstruction. Agonism of GnRH receptors initially results in the stimulation of luteinizing hormone LH and follicle-stimulating hormone FSH secretion by the anterior pituitary ultimately leading to increased serum estradiol and testosterone levels via the normal physiology of the hypothalamic—pituitary—gonadal axis HPG axis ; however, because propagation of the HPG axis is incumbent upon pulsatile hypothalamic GnRH secretion, pituitary GnRH receptors become desensitised after several weeks of continuous leuprorelin therapy. No patient discontinued therapy due to an injection site adverse event.

Leuprolide injection is a synthetic man-made hormone that is similar to a natural hormone that is produced in the brain. It is used to treat a number of medical problems including:. It is also used together with iron to treat bleeding in women with anemia caused by uterine leiomyomas before a surgical procedure.

LiverTox toxicity likelihood category E. Elsevier Health Sciences. Leuprolide English. Pill Size mm? Veterinary use. Can you list the top facts and stats about Leuprorelin? Expected hormonal changes that occur with ELIGARD treatment increase the risk for pregnancy loss and fetal harm when administered to a pregnant women. It may be used to reduce the risk of premature ovarian failure in women receiving cyclophosphamide for chemotherapy. Castrate levels were generally reached within two to four weeks. Chicago Tribune. Decreased red blood cell count , hematocrit and hemoglobin. Archived PDF from the original on 10 April Adis Insight.

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