Robitussin moa

Dextromethorphan DXM is a cough suppressant used in many cough and cold medicines. It is in the robitussin moa moxxies of medications with sedativedissociativeand robitussin moa properties at lower doses. Dextromethorphan does not have a significant affinity for the mu-opioid receptor activity typical of morphinan compounds and exerts its therapeutic effects through several other receptors. When exceeding approved dosages, robitussin moa, dextromethorphan acts as a dissociative hallucinogen.

Federal government websites often end in. Before sharing sensitive information, make sure you're on a federal government site. The site is secure. NCBI Bookshelf. Dextromethorphan received FDA approval in for its use as a cough suppressant.

Robitussin moa

Manufacturer: Interphil. Full Prescribing Info. Formulation: See Table 1. This medicine contains the active ingredients Dextromethorphan Hydrobromide, a cough suppressant and Guaifenesin, an expectorant. Robitussin DM temporarily relieves cough due to minor throat and bronchial irritation as may occur with a cold and expectorant actions to help loosen phlegm and thin bronchial secretion to make cough more productive. It also helps relieve chest congestion. See Table 2. Take the missed dose as soon as the patient remembers. However, if it is almost time for the next dose, skip the missed dose and continue the regular dosing schedule. Do not take double dose to make up for the missed one. Nausea and vomiting; depressed level of consciousness, dizziness, dysarthria speech difficulty , myoclonus involuntary muscle twitching , nystagmus involuntary eyeball motion , somnolence, tremors; excitability, confusional state, psychotic disorder; respiratory depression. In case of accidental overdose, discontinue use and seek professional assistance immediately.

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Robitussin DM can help reduce cough and loosen phlegm. It may interact with some medications, including those for certain psychiatric conditions. Robitussin DM is a cough medicine for treating your cold or flu. Robitussin DM is used to temporarily relieve your cough from minor throat irritation or a cold. It also helps loosen phlegm from chest congestion so that you can cough it up and spit it out.

Federal government websites often end in. Before sharing sensitive information, make sure you're on a federal government site. The site is secure. NCBI Bookshelf. Dextromethorphan received FDA approval in for its use as a cough suppressant. It is one of the most common compounds found in most over-the-counter antitussives for the past 50 years. In , the FDA approved the use of dextromethorphan for pseudobulbar affect in combination with quinidine.

Robitussin moa

Dextromethorphan DXM is a cough suppressant used in many cough and cold medicines. It is in the morphinan class of medications with sedative , dissociative , and stimulant properties at lower doses. Dextromethorphan does not have a significant affinity for the mu-opioid receptor activity typical of morphinan compounds and exerts its therapeutic effects through several other receptors. When exceeding approved dosages, dextromethorphan acts as a dissociative hallucinogen. It has multiple mechanisms of action , including actions as a nonselective serotonin reuptake inhibitor [9] and a sigma-1 receptor agonist. It was patented in and approved for medical use in The primary use of dextromethorphan is as a cough suppressant , for the temporary relief of cough caused by minor throat and bronchial irritation such as commonly accompanies the flu and common cold , or from inhaled particle irritants, as well as chronic cough at a higher dosage. Dextromethorphan is the actual therapeutic agent in the combination; quinidine merely serves to inhibit the enzymatic degradation of dextromethorphan and thereby increase its circulating concentrations via inhibition of CYP2D6. Because dextromethorphan can trigger a histamine release allergic reaction , atopic children, who are especially susceptible to allergic reactions, should be administered dextromethorphan only if absolutely necessary, and only under the strict supervision of a healthcare professional.

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What special dietary instructions should I follow? International Society for the Study of Cough. Stroke: Studies have shown that DM has a role in the improvement of some neurological and psychiatric complications, however, not the overall functional outcomes. Dextromethorphan is well tolerated and has a wide therapeutic window, making it an amenable drug for clinical use. Search term. June Archived PDF from the original on 21 August This loss of control disrupts inhibitory mechanisms for motor control of emotional expression. Pregnant Women: It is considered as pregnancy category C medicine. It is usually taken every 4 to 12 hours as needed. However, you should not flush this medication down the toilet. It is also important information to carry with you in case of emergencies. A large number of medications are potent inhibitors of CYP2D6. Access free multiple choice questions on this topic.

Excipient information presented when available limited, particularly for generics ; consult specific product labeling. ElixSure Cough: 7.

Register or sign in to continue. NCBI Bookshelf. Dextromethorphan also undergoes N-demethylation to 3-methoxymorphinan or MEM , [37] and partial conjugation with glucuronic acid and sulfate ions. R05FA02 - opium derivatives and expectorants ; Belongs to the class of combinations of opium derivatives cough suppressants and expectorants. In , Romilar was taken off the shelves after a burst in sales because of frequent misuse. Guaifenesin belongs to a class of drugs called expectorants. Drug Metabolism and Disposition. Sigma receptor modulators. Careful documentation of past medical history and current medications is crucial in diagnosing one of its major overdose complications. Wikimedia Commons. A number of other CYP enzymes are implicated as minor pathways of dextromethorphan metabolism. Robitussin DM comes in a liquid form that you take by mouth. Morphinan antitussive and dissociative drug.