Rp h10 325 pill

Limitations of Use Because of the risks of addiction, abuse, and misuse with opioids, which can occur at any dosage or duration [see WARNINGS ]reserve hydrocodone bitartrate and acetaminophen tablets for use in patients for whom alternative treatment options e.

Go PRO to access past versions. If opioid use is required for an extended period of time in a pregnant woman, advise the patient of the risk of NOWS, which may be life-threatening if not recognized and treated. Use of hydrocodone bitartrate and acetaminophen tablets for an extended period of time during pregnancy can result in withdrawal in the neonate. Neonatal opioid withdrawal syndrome, unlike opioid withdrawal syndrome in adults, may be life-threatening if not recognized and treated, and requires management according to protocols developed by neonatology experts. Observe newborns for signs of neonatal opioid withdrawal syndrome and manage accordingly. Advise pregnant women using opioids for an extended period of time of the risk of neonatal opioid withdrawal syndrome and ensure that appropriate treatment will be available Use of hydrocodone bitartrate and acetaminophen tablets for an extended period of time during pregnancy can result in withdrawal in the neonate. Advise nursing mothers to carefully observe infants for increased sleepiness more than usual , breathing difficulties, or limpness.

Rp h10 325 pill

If you are a consumer or patient please visit this version. Hydrocodone bitartrate is an opioid analgesic and antitussive and occurs as fine, white crystals or as a crystalline powder. It is affected by light. It has the following structural formula:. Acetaminophen, 4'-hydroxyacetanilide, a slightly bitter, white, odorless, crystalline powder, is a non-opiate, non-salicylate analgesic and antipyretic. In addition, each tablet contains the following inactive ingredients: colloidal silicon dioxide, crospovidone, magnesium stearate, microcrystalline cellulose, povidone, pregelatinized starch and stearic acid. Hydrocodone is a semisynthetic opioid analgesic and antitussive with multiple actions qualitatively similar to those of codeine. Most of these involve the central nervous system and smooth muscle. The precise mechanism of action of hydrocodone and other opiates is not known, although it is believed to relate to the existence of opiate receptors in the central nervous system. In addition to analgesia, opioids may produce drowsiness, changes in mood and mental clouding. The analgesic action of acetaminophen involves peripheral influences, but the specific mechanism is as yet undetermined. Antipyretic activity is mediated through hypothalamic heat regulating centers. Acetaminophen inhibits prostaglandin synthetase.

Medical literature suggests a strong biologic plausibility between opioid analgesics and OIH and allodynia. Adrenal Insufficiency Inform patients that hydrocodone bitartrate and acetaminophen tablets could cause adrenal insufficiency, a potentially life-threatening condition.

Because the use of hydrocodone bitartrate and acetaminophen tablets expose patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death, assess each patient's risk prior to prescribing and reassess all patients regularly for the development of these behaviors and conditions [see WARNINGS ]. Serious, life-threatening, or fatal respiratory depression may occur with use of hydrocodone bitartrate and acetaminophen tablets, especially during initiation or following a dose increase. To reduce the risk of respiratory depression, proper dosing and titration of hydrocodone bitartrate and acetaminophen tablets are essential [see WARNINGS ]. Accidental ingestion of even one dose of hydrocodone bitartrate and acetaminophen tablets, especially by children, can result in a fatal overdose of hydrocodone [see WARNINGS ]. Concomitant use of opioids with benzodiazepines or other central nervous system CNS depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death. If opioid use is required for an extended period of time in a pregnant woman, advise the patient of the risk of NOWS, which may be life-threatening if not recognized and treated. The concomitant use of hydrocodone bitartrate and acetaminophen tablets with all Cytochrome P 3A4 inhibitors may result in an increase in hydrocodone plasma concentrations, which could increase or prolong adverse reactions and may cause potentially fatal respiratory depression.

If you are looking for a drug that is pure and potent, then Oxycodone Hydrochloride 10 mg may be the answer. It should not be used by those who have ever had asthma or difficulty breathing with other medicines. Oxycodone is a narcotic analgesic that belongs to the class of drugs called narcotic analgesics. The pill with the imprint of RP 10 is white, round, and contains acetaminophen and oxycodone hydrochloride. It comes from Rhodes Pharmaceuticals L. That means it can only be used under close medical supervision. The White RP 10mg oxycodone is an opioid agonist.

Rp h10 325 pill

The dose and duration will depend on your condition and how well it helps your pain to go. It can be taken by most adults and even children if prescribed by a doctor. If used in late pregnancy, your child may be born with withdrawal symptoms and other mild to moderate complications. Swallow this pill as a whole with a glass of water or a choice of non-alcoholic drink.

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If one is not available, you can dispose of oxycodone and acetaminophen tablets by mixing the product with dirt, cat litter, or coffee grounds; placing the mixture in a sealed plastic bag, and throwing the bag in your trash. Procedures to limit the continuing absorption of the drug must be readily performed since the hepatic injury is dose dependent and occurs early in the course of intoxication. Effects on the Gastrointestinal Tract and Other Smooth Muscle Hydrocodone causes a reduction in motility associated with an increase in smooth muscle tone in the antrum of the stomach and duodenum. For more information, go to dailymed. Benzodiazepines and other CNS Depressants Due to additive pharmacologic effect, the concomitant use of benzodiazepines and other CNS depressants, such as benzodiazepines and other sedative hypnotics, anxiolytics, tranquilizers, muscle relaxants, general anesthetics, antipsychotics, and other opioids, including alcohol, can increase the risk of hypotension, respiratory depression, profound sedation, coma, and death. Hyperalgesia and Allodynia Inform patients and caregivers not to increase opioid dosage without first consulting a clinician. Evaluate patients at frequent intervals for respiratory depression and sedation. Hydrocodone produces respiratory depression by direct action on brain stem respiratory centers. Are pregnant or planning to become pregnant. Taking hydrocodone bitartrate and acetaminophen tablets with other opioid medicines, benzodiazepines, alcohol, or other central nervous system depressants including street drugs can cause severe drowsiness, decreased awareness, breathing problems, coma, and death. Call your doctor to receive medical advice. Important Dosage and Administration Instructions Hydrocodone bitartrate and acetaminophen tablets should be prescribed only by healthcare professionals who are knowledgeable about the use of opioids and how to mitigate the associated risks.

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Life-Threatening Respiratory Depression Serious, life-threatening, or fatal respiratory depression may occur with use of hydrocodone bitartrate and acetaminophen tablets, especially during initiation or following a dose increase. Inform patients that they can visit www. Observe newborns for signs of neonatal opioid withdrawal syndrome and manage accordingly. The total daily dosage should not exceed 8 tablets. Drink alcohol or use prescription or over-the-counter medicines that contain alcohol. If hypoprothrombinemia occurs due to acetaminophen overdose, vitamin K should be administered intravenously. In addition, discontinuation of a concomitantly used Cytochrome P 3A4 inducer may result in an increase in hydrocodone plasma concentrations. While taking hydrocodone bitartrate and acetaminophen tablets DO NOT: Drive or operate heavy machinery, until you know how hydrocodone bitartrate and acetaminophen tablets affect you. Hydrocodone bitartrate and acetaminophen tablets, like other opioids, can be diverted for nonmedical use into illicit channels of distribution. All patients treated with opioids require careful and frequent reevaluation for signs of misuse, abuse, and addiction, because use of opioid analgesic products carries the risk of addiction even under appropriate medical use. Good clinical practice dictates a patient-specific plan to taper the dose of the opioid gradually. In severe overdosage, apnea, circulatory collapse, cardiac arrest and death may occur.