White oval pill with 377

Tramadol is a prescription medication used to treat moderate to moderately severe pain in adults. Tramadol belongs to a group of drugs called opioid analgesics, which work by blocking pain signals in the body.

If you are a consumer or patient please visit this version. Dosage and Administration 2. Warnings and Precautions 5. Tramadol hydrochloride tablets are an opioid agonist indicated in adults for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate 1. Limitations of Use 1. Because of the risks of addiction, abuse, and misuse with opioids, which can occur at any dosage or duration, reserve tramadol hydrochloride tablets for use in patients for whom alternative treatment options [e. Life-Threatening Respiratory Depression.

White oval pill with 377

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Because of the risks of addiction, abuse, and misuse with opioids, which can occur at any dosage or duration, reserve tramadol hydrochloride tablets for use in patients for whom alternative treatment options [e. If no take back programs or Drug Enforcement Administration DEA -registered collectors are available, instruct patients to dispose of tramadol hydrochloride tablets by following these four steps:.

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The white elliptical pill with the imprint has been identified as Tramadol Hydrochloride 50 mg supplied by Sun Pharmaceutical Industries Inc.. The tramadol pill is a prescription drug and belongs to the drug class narcotic analgesics. This pill is a controlled substance. The company was founded in and has been continuously family-owned. The pill is used to relieve moderate to moderately severe pain works by changing how your brain senses pain. Endorphins bind to receptors parts of cells that receive a certain substance.

White oval pill with 377

Learn about the medical, dental, pharmacy, behavioral, and voluntary benefits your employer may offer. Keep this medicine where others cannot get to it. Tramadol should not be given to a child younger than 12 years old, or anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

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A dose of mg tramadol hydrochloride tablets tended to provide analgesia superior to codeine sulfate 60 mg, but it was not as effective as the combination of aspirin mg with codeine phosphate 60 mg. Overestimating the tramadol hydrochloride tablets dosage when converting patients from another opioid product can result in a fatal overdose with the first dose. Strategies to reduce these risks include prescribing the drug in the smallest appropriate quantity and advising the patient on careful storage of the drug during the course of treatment and the proper disposal of unused drug. Lactation : Breastfeeding not recommended 8. Based upon postmarketing reports with tramadol or with codeine, children younger than 12 years of age may be more susceptible to the respiratory depressant effects of tramadol. If a CYP3A4 inhibitor is discontinued, consider increasing the tramadol hydrochloride tablets dosage until stable drug effects are achieved and evaluate patients at frequent intervals for signs and symptoms of opioid withdrawal. Formation of M1 is dependent on CYP2D6 and as such is subject to inhibition, which may affect the therapeutic response [ see Warnings and Precautions 5. Inform female patients of reproductive potential that tramadol hydrochloride tablets may cause fetal harm and to inform the healthcare provider of a known or suspected pregnancy [see Use in Specific Populations 8. If a CYP3A4 inducer is discontinued, consider tramadol hydrochloride tablets dose reduction and evaluate patients at frequent intervals for signs of respiratory depression and sedation. Tramadol falls into category C. Tramadol is subject to the same polymorphic metabolism as codeine, with ultra-rapid metabolizers of CYP2D6 substrates being potentially exposed to life-threatening levels of the active metabolite O -desmethyltramadol M1. Tramadol was evaluated in pre- and post-natal studies in rats.

Tramadol hydrochloride is the active ingredient present in this pill. It is available in the form of a tablet and belongs to a category of drug called narcotic analgesics, which block the signals causing pain in any part of the body.

In a randomized, blinded clinical study with to patients per group, a day titration to a daily tramadol hydrochloride tablets dose of mg 50 mg four times per day , attained in 50 mg increments every 3 days, was found to result in fewer discontinuations due to dizziness or vertigo than titration over only 4 days or no titration. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to regularly evaluate renal function. Avoid the use of tramadol hydrochloride tablets in adolescents 12 to 18 years of age who have other risk factors that may increase their sensitivity to the respiratory depressant effects of tramadol. Did you experience many side effects while taking this drug? CYP2D6 is a protein in your body that is involved in the elimination of tramadol and other drugs from your body. Hepatic Impaired, 50 mg SD p. Product Information. A multimodal approach to pain management may optimize the treatment of chronic pain, as well as assist with the successful tapering of the opioid analgesic [see Warnings and Precautions 5. Drink alcohol or use prescription or over-the-counter medicines that contain alcohol. View Package Photos. Opioids are sought for nonmedical use and are subject to diversion from legitimate prescribed use. Life-Threatening Respiratory Depression Serious, life-threatening, or fatal respiratory depression may occur with use of tramadol hydrochloride tablets, especially during initiation or following a dosage increase. Advise patients how to recognize such a reaction and when to seek medical attention [see Contraindications 4 ; Warnings and Precautions 5. These individuals convert tramadol into its active metabolite, O -desmethyltramadol M1 , more rapidly and completely than other people.