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Acetaminophen and oxycodone is a combination medicine used to relieve moderate to severe pain. Acetaminophen and oxycodone may also be used for purposes not listed in this medication guide.

Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed milligrams per day, and often involve more than one acetaminophen-containing product. Each tablet, for oral administration, contains oxycodone hydrochloride and acetaminophen in the following strengths:. All strengths of oxycodone and acetaminophen tablets USP also contain the following inactive ingredients: crospovidone, microcrystalline cellulose, povidone, pregelatinized starch, silicon dioxide and stearic acid. It is derived from the opium alkaloid thebaine. Oxycodone hydrochloride may be represented by the following structural formula:.

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If you are a consumer or patient please visit this version. Liver warning: This product contains acetaminophen. Severe liver damage may occur if. Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:. Do not use with any other drug containing acetaminophen prescription or nonprescription. If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. Ask a doctor or pharmacist before use if the user is taking the blood thinning drug warfarin. If pregnant or breast-feeding, ask a health professional before use. Overdose warning: Taking more than the recommended dose overdose may cause liver damage.

How does this medication work?

Acetaminophen belongs to a group of medicines called analgesics pain relievers and antipyretics fever reducers. It works quickly to relieve pain caused by conditions such as headache and osteoarthritis, and to reduce fever caused by infection. Unlike acetylsalicylic acid ASA , which is also an analgesic and antipyretic, acetaminophen does not reduce inflammation. Acetaminophen is used by itself as well as in combination medication products for cough, cold, and pain relief. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Acetaminophen and oxycodone is a combination medicine used to relieve moderate to severe pain. Acetaminophen and oxycodone may also be used for purposes not listed in this medication guide. Acetaminophen and oxycodone contains an opioide medicine and may be habit-forming. You should not use this medicine if you are allergic to acetaminophen or oxycodone, or if you have:. If you use opioid medicine while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on opioids may need medical treatment for several weeks.

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It is available as a prescription only medicine and is commonly used for Chronic Pain, Pain. Exercise has many benefits for older adults and can help you to live a longer and healthier life. Here are 6 benefits of exercise for older adults and seniors. Natural home remedies and over-the-counter OTC products can be used to temporarily relieve toothache pain until you can visit your dentist. Certain over-the-counter pain medications can be used alongside antibiotics and other self care options to help alleviate the pain caused by a UTI. CBD cannabidiol is a chemical found in the Cannabis sativa plant, which is being investigated for its potential health benefits.

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Drug addiction is defined as an abnormal, compulsive use, use for non-medical purposes of a substance despite physical, psychological, occupational or interpersonal difficulties resulting from such use, and continued use despite harm or risk of harm. Acetaminophen USP, mg. Pediatric Use Safety and effectiveness in pediatric patients have not been established. Taking certain medications together can lead to a fatal overdose. Common side effects include: This is not a complete list of side effects and others may occur. Health Conditions A-Z. Inactive Ingredients. Early symptoms following a potentially hepatotoxic overdose may include: nausea, vomiting, diaphoresis, and general malaise. Call your doctor if you took more than the recommended dose. Depending on your specific circumstances, your doctor may want you to:. Physical dependence on a prescribed medication does not signify addiction. Dispense in a tight, light-resistant container as defined in the USP, with a child-resistant closure as required.

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Drug addiction is defined as an abnormal, compulsive use, use for non-medical purposes of a substance despite physical, psychological, occupational or interpersonal difficulties resulting from such use, and continued use despite harm or risk of harm. Keep the medication out of the reach of children, use an oral syringe to measure the dose, read the package carefully, and consult your pharmacist or doctor to confirm the best dose for your child. In severe overdosage, apnea, circulatory collapse, cardiac arrest, and death may occur. Dosage should be adjusted according to the severity of the pain and the response of the patient. You should not use this medicine if you are allergic to acetaminophen or oxycodone, or if you have: If you use opioid medicine while you are pregnant, your baby could become dependent on the drug. Probenecid — Probenecid may increase the therapeutic effectiveness of acetaminophen slightly. Take only one product that contains acetaminophen at a time. If you develop signs of allergy such as a rash or difficulty breathing stop taking oxycodone and acetaminophen tablets USP and contact your healthcare provider immediately. Selling or giving away opioid medicine is against the law. A high portion of oxycodone is N-dealkylated to noroxycodone during first-pass metabolism. What other drugs will affect acetaminophen and oxycodone?